When Adam finds out he has cancer, he’s shocked. 50/50 tells the story of how Adam, a young man, learns to deal with his diagnosis while facing fears, friendships, and life changes. It’s a film about navigating the unexpected with humor, heart, and the support of those closest to you.

A key moment happens when Adam’s best friend, Kyle, supports him in an unexpected way. Kyle, while trying to help Adam get through the rough parts, ends up making Adam feel both loved and annoyed in a hilarious, yet emotional, scene.

Some fan theories suggest that Kyle, who seems to be an over-the-top jokester, actually uses humor as his way of coping with fear and anxiety about his own life. What if Kyle’s jokes were a shield for his own deeper feelings? Would he have been different if Adam had never gotten sick?

In an alternate ending, Adam’s recovery could have been longer, or maybe even more uncertain, showing that not every story has to end neatly. A prequel could explore Adam’s life before his diagnosis, focusing on his relationship with his mom, girlfriend, and friends, and how those connections set the foundation for the strength he would need later.